The inhibitors of the reuptake of serotonin such as, for instance, Fluoxetine and Paroxetine significantly influence the effectiveness and other medicines that inhibit the CYP2D6 enzyme. They increase the maximum concentration of the drug in the blood 3-4 fold. Therefore, it is recommended to raise the dose of Atomoxetine with greater intervals and reduce the final maintenance dose from the original recommended if the concurrent therapy is appointed. If the appointment of the inhibitors of the said enzyme happens before or after the Atomoxetine dose adjustments, the clinical response and tolerance of the substance should be checked again in every particular patient to assess the need of the dose correction.
The preparation should be used with caution in people who receive high doses of Salbutamol or other beta 2-agonists in aerosol form or for systemic administration since the effect of Salbutamol on the cardiovascular system may be enhanced. The Strattera must be also cautiously used with any medications aimed to lower the arterial pressure because Strattera can lower their effectiveness. People with hypertension must control their blood pressure regularly throughout the therapy and their doctors should adjust the doses of antihypertensive drugs respectively based on their effect with Strattera. The medications that cause the narrowing of the blood vessels and increase the arterial pressure should be cautiously used with Atomoxetine-based medications since they also elevate the blood pressure.
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How must Generic Strattera be used? It is advised to address doctors who have sufficient experience treating ADHD in children and adolescents in particular. If an adult patient wants to use the medication, a doctor must learn his or her health history to make sure that the diagnosis was made in childhood or adolescence and is correct. It is not recommended to start the therapy with the drug if there is no proof of the condition presence in childhood or adolescence. Besides, the diagnosis must not be established if there are only one or two symptoms of the disorder, they are not of moderate severity at least, and do not include violations in the social, learning, or professional activities.
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