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As a vermicidal, albendazole causes degenerative alterations in the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting its polymerization or assembly into microtubules. The loss of the cytoplasmic microtubules leads to impaired uptake of glucose by the larval and adult stages of the susceptible parasites, and depletes their glycogen stores. Degenerative changes in the endoplasmic reticulum, the mitochondria of the germinal layer, and the subsequent release of lysosomes result in decreased production of adenosine triphosphate ATP , which is the energy required for the survival of the helminth. Due to diminished energy production, the parasite is immobilized and eventually dies.
This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details. Before using this medication, tell your doctor or pharmacist your medical history, especially of: It works preventing absorbing sugar. As a result infection loses energy and dies. Directions It is recommended to take the medicine as it was prescribed by your doctor. Swallow pill the whole. Take it with meal two times per day. Precautions Before starting your treatment with Albenza tell you doctor if you have eye problems, liver failure, low white blood cell counts, low platelet counts, or bone marrow problems.
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